WeedLife News Network

Hot off the press cannabis, marijuana, cbd and hemp news from around the world on the WeedLife Social Network.

Long Beach expands cannabis social equity program

The Long Beach City Council this week voted to allow more cannabis dispensaries and delivery-only marijuana businesses, but asked staff to figure out how to pay for the expanded program without raising taxes.

“It could potentially cripple the businesses we’re trying to lift up,” Councilman Al Austin said about the rejected tax increase. “That’s my real concern.”

The city’s social equity program was created in 2018 to allow those who were targeted for cannabis-related crimes to benefit from legalization.

The ordinance will allow eight more dispensaries to operate in Long Beach, exclusive to those who qualify for the equity program.

To decide these new eight business owners, city staff would implement a merit-based lottery, meaning applicants would go through an interview process first and eligible candidates would be picked randomly. But that process was questioned by council members, too, with some asking for a process that does not include a lottery.

To qualify, equity applicants must meet one of the following requirements:

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Many adults with breast cancer use cannabis but don’t tell their doctors

Almost half of US adults with breast cancer use cannabis (marijuana and hemp), most commonly in combination with cancer treatment to control symptoms and side effects, according to a new study. However, most patients do not discuss cannabis use with their doctor. The findings will be published online early. cancer..

Individual cancer People often experience pain, malaise, nausea, and other difficulties that result from cancer and its treatment. While some rely on cannabis to relieve symptoms, many doctors feel that they lack the knowledge they need to discuss cannabis with their patients. Such knowledge is especially important now that cancer is designated as a qualifying condition in almost every state. Medical cannabis program.

Investigators recently conducted an anonymous online survey to investigate cannabis use in diagnosed adults. breast cancer Within five years, he was a member of the Breastcancer.org and Healthline.com online health communities.

 

Among the main findings:

Of the total of 612 participants, 42% reported using cannabis to relieve symptoms such as pain, insomnia, anxiety, stress, and nausea / vomiting. Seventy-five percent of people who used cannabis reported that cannabis was very or very helpful in relieving symptoms.Almost half (49%) of participants who used cannabis believed that medical cannabis could be used to treat the cancer itself. However, its effectiveness against cancer is unknown.Of those who use cannabis, 79% used cannabis during treatments such as systemic therapy, radiation therapy, and surgery.Participants reported using a variety of cannabis products known to differ in quality and purity.Half of the participants asked for information about medical cannabis, and the website and other patients were ranked as the most useful sources of information. The doctor was ranked lower in the list.Among those who asked for information Use of cannabis For medical purposes, most people were not happy with the information they received.Most participants believed that cannabis products were safe and were unaware that many products had not been tested for safety.

“Our research highlights an important opportunity for providers to start informed conversations about medical cannabis with patients. Evidence shows that many people use medical cannabis without our knowledge and guidance. “It shows that,” said Dr. Marisa Weiss, lead author of Breastcancer.org. Rankenau Medical Center near Philadelphia, Pennsylvania. “Not knowing if our cancer patients are using cannabis is a major blind spot in our ability to provide optimal treatment, and as a healthcare provider, we talk about medical cannabis with patients. You need to do a better job of initiating informed conversations Those symptoms and side effects are well managed and regarding potential side effects, therapeutic interactions, or the use of medical cannabis for the treatment of cancer. We minimize the risk of non-compliance with standard treatment due to incorrect information. “

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Medical marijuana in Illinois: 5 things to know about increase in cannabis registrations

Through the first nine months of this year Illinois has already far exceeded the more than $669 million it did in adult-use recreational cannabis sales in 2020.

September sales totaled $121,717,709.51, compared to the $67,648,362.14 in statewide sales in September 2020.

The monthly report the Illinois Department of Financial and Professional Regulation released this week shows $997,067,100.34 in recreational cannabis sales through the first nine months of this year.

Illinois driver's licenses: 5 things to know about Illinois driver’s licenses, Real ID cards and the digital future

In addition to the significant increase in recreational cannabis sales over the last year, the number of Illinoisans registered for medical marijuana has also continued to grow by a large margin each year.

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Eight-year-old rushed to hospital after consuming cannabis edibles

An eight-year-old Woodstock child ate a large quantity of cannabis gummies over the weekend. The child was rushed to hospital and was in stable condition. Woodstock police wanted to remind people who consume cannabis, particularly edibles such as gummies or other sweets, to be mindful of safe storage away from children. Police encourage adults to safely store any alcohol and cannabis products out of reach or behind locked doors to ensure children do not consume them by mistake.

In the summer of 2020, Health Canada issued an advisory that children are being harmed after consuming illegal cannabis edibles that are not subject to safety and quality controls, do not have childproof packaging and have been stored by parents in places too easily accessible to kids. The caution was issued following several cases of children having been hospitalized after ingesting illegal weed edibles that looked like regular candies or treats.

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New Research on Genetically Susceptible Mice Shows THC/Cannabis Causes Birth Defects

Cannabis, also known as weed or marijuana, is used by hundreds of millions of people worldwide. Although restricted in most countries, the increasing legalization of cannabis for recreational and medicinal consumption means that cannabis use is rising. Cannabis is also the most common illicit drug used by pregnant women, but the effects of cannabis on embryonic development are not well understood. It is also important to understand the effects of cannabis on individuals with a genetic predisposition, which means they carry genetic mutations that increase the risk of environmental conditions triggering a defect or disease.

A new study from scientists at the Icahn School of Medicine at Mount Sinai, USA, has now revealed that THC, the chemical in cannabis that causes the sensation of feeling ‘high’, can cause birth defects in genetically predisposed mice. In this case, the researchers investigated whether THC could exacerbate a mutation that affects a mechanism that cells use to communicate with each other, called Hedgehog signaling. “Several years ago, it was reported that THC could inhibit Hedgehog signaling in cells grown in a dish,” said the study’s lead author Robert Krauss, PhD, Professor of Cell, Developmental and Regenerative Biology at the Icahn School of Medicine at Mount Sinai. “We reasoned that THC might be an environmental risk factor for birth defects, but that it would require additional risk factors, such as specific mutations in the genes required for Hedgehog signaling, to induce these defects in mice.”

To address this hypothesis, Dr. Krauss and colleagues administered a single dose of THC, equivalent to exposures achieved when humans smoke cannabis, to pregnant mice about a week after conception. They then studied the embryonic development of their pups, some of which carried a mutation that meant Hedgehog signaling was not functioning at full efficiency. The scientists found that pups without the mutation developed normally, even when exposed to THC, as did pups that carried the mutation but were not exposed to the drug. However, pups that were exposed to THC and carried the mutation developed a brain and face defect called holoprosencephaly, a common birth defect seen in 1 in 250 human conceptions that includes the failure of the forebrain to divide into two distinct segments.

The researchers showed that the defect occurs because THC can interfere with Hedgehog signaling in the embryo. THC alone is not sufficient to disrupt Hedgehog signaling and cause defects but, in animals where Hedgehog signaling is already weakened through genetic mutation, it has significant effects. “THC directly inhibits Hedgehog signaling in mice, but it is not a very powerful inhibitor; this is presumably why a genetic predisposition is required for it to cause holoprosencephaly in mice,” explained Dr. Krauss.

These first studies in mice have important implications for human health, highlighting the need for more research into the effects of cannabis use during pregnancy in humans. “The THC concentration in cannabis is now very high, so it is important to perform epidemiology studies looking at whether cannabis consumption is associated with developmental defects. Women are already advised not to consume cannabis while pregnant, but our results show that embryos are sensitive at a very early period, before many women know they are pregnant. Cannabis consumption may therefore be inadvisable even when women are trying to get pregnant,” Dr. Krauss warned.

Although this study focussed on one chemical in cannabis and one genetic mutation, further research could reveal other combinations that cause similar effects. “Many of the mutations found in human holoprosencephaly patients could conceivably synergize with THC,” said Dr. Krauss. “We would also like to test the related chemical CBD in genetically predisposed mice. Like THC, CBD inhibits Hedgehog signaling in cells grown in a dish, but CBD appears to work differently. As CBD is widely available and often viewed as beneficial – or at least innocuous – it would be worth investigating this as well,” he added.

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Analysis from CBD Oracle suggests most CBD manufacturers make effort at transparency

CBD Oracle (Tustin, CA), a cannabis review and news site, has published an analysis of 520 CBD companies, representing over 20,000 products. The study sought to uncover issues with transparency in the unregulated CBD marketplace, which can threaten consumer trust. According to a survey from Consumer Brands Association, 92% of American consumers either incorrectly assume or have no idea if CBD is federally regulated. Upon being informed that there are no federal agencies that regulate CBD products, 84% of respondents expressed concern about the safety of CBD products. 

CBD Oracle’s study offers an optimistic view of the industry. According to its findings, 89.4% of companies test their CBD products through accredited third-party labs, demonstrating a transparent industry. “Despite consumer apprehension being a huge problem, our analysis suggests an industry so conscious of its regulatory shortcomings it’s taking appropriate steps to fix them,” said Alisdair Mans Cornwell, senior editor at CBD Oracle, in a statement.

Additional findings showed that 89% of companies fully disclose their hemp source and cultivation practices. Most of U.S. hemp sourced for CBD products came from Colorado (30.1%), followed by Oregon (13.4%), then Kentucky and California (tied for 5.1%). Eight percent of hemp was source from Europe, according to the study. The most popular European sources of hemp were Holland, Lithuania, Switzerland, and Spain.

When it came to the most common type of CBD products offered, the majority of companies (72%) sell some type of CBD tincture. The second most popular option sold was topical CBD, offered by 65% of the companies in the analysis. The third and fourth most popular options were capsules and gummies, sold by 42% and 40% of companies, respectively. Unfortunately, 43% of CBD companies in the study did not disclose extraction methods used for their products. Of those that did disclose extraction methods, CO2 extraction was used by 42% of CBD companies, with ethanol extraction being the second most popular method (11%).

CBD Oracle also collected data about minor cannabinoids. According to its analysis, the most popular minor cannabinoid present in the marketplace is cannabigerol (CBG), sold by 20% of the 520 companies. This was followed by cannabinol (CBN), sold by 12% of the companies, and delta-8 THC, sold by 10% of the companies. CBD Oracle expected more companies to sell delta-8 THC. It cites data from New Fronteir Data that states sales of delta-8 THC has reached $10 million across the U.S. in 2020. Despite the exponential market growth of delta-8, CBD Oracle believes that restrictions on the sale of the minor cannabinoid across 19 states is likely contributing to relatively low adoption of delta-8 by manufacturers.

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The best CBD for cats

 

It’s not always easy to tell when your feline is stressed, but cats can be as anxiety-prone as people. Additionally, many aging cats start to experience joint pain and overall discomfort caused by conditions such as arthritis.

CBD products can offer a plethora of benefits to your furry friend. If you're looking for a great CBD product to soothe your cat, Cornbread CBD Oil for Pets works excellently for calming anxious behaviors. What to know before you buy CBD for cats

Effectiveness

Many humans have begun turning to CBD to relieve joint and back pain, anxiety, sleeplessness and various inflammatory issues. As such, it isn't surprising that the market for pets has grown significantly. There aren't many conclusive studies about the effects of CBD, but one 2016 Israeli study linked CBD oil to a decrease in seizure frequency for children. Animals can be prone to seizures too, so the study bodes well for epileptic pets.

Illness 

CBD for cats can treat a number of physical and emotional conditions. Inflammatory conditions like arthritis can be eased with CBD. The same may be true for cats with seizures and cats recovering from surgical procedures. CBD can even work for digestive issues, as it can reduce swelling in a cat’s digestive tract and improve overall discomfort. CBD is equally as popular for treating behavioral issues, the two major ones being anxiety and aggression. Since CBD interacts with endocannabinoids, which affect mood, CBD can help regulate and stabilize mood.

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Why Does Marijuana Make Some People Faint?

While most people can use marijuana without experiencing any issues whatsoever, fainting is a side effect that has been known to happen. Some medical experts say these blackout moments can occur since THC decreases blood pressure in the body.(As Originally Seen On Benzinga)

One second you’re at a party, laughing it up with friends like you’ve done a thousand times before when a joint makes its way into your hands. Nothing out of the ordinary here, except for the fact that by smoking with others, you are about to contract the germs of everyone else in the room, but that’s another story for another time. In this particular scenario, however, you take a hit off the joint, pass it to the left and continue to bask in the conversation going on around you.  

But then all of a sudden, things start to get weird.

You might feel at first as if you are going to vomit, and your senses might start going a bit haywire. You might even have some trouble catching your breath, saying something to the person next to you, like “Dang, what was in that weed.” You even consider excusing yourself for a minute to regain your faculties, but before you have any chance to make it to the bathroom, everything goes black. You are told later that you just dropped out completely after taking that hit of weed. 

Unfortunately, while most people can use marijuana without experiencing any issues whatsoever, fainting is a side effect that has been known to happen. Some medical experts say these blackout moments can sometimes occur since tetrahydrocannabinol (THC), the cannabinoid that produces the herb’s stoned effects, expands the blood vessels, which decreases blood pressure in the body. When this happens, the heart rate increases, and it can cause people to lose consciousness.  

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Illinois Women in Cannabis to Host a Breast Cancer and Cannabis Conversation

Illinois Women in Cannabis to Host a Breast Cancer and Cannabis Conversation; Virtual Forum Contributes to October’s Annual Breast Cancer Awareness Month  Free Oct. 6 Webinar Features Midwest Cancer & Cannabis Clinicians and Patients, and is sponsored by NuEra Cannabis, in honor of its “Pre-Rolls for a Cause” Campaign

Illinois Women in Cannabis (IWC), the state’s leading cannabis industry networking organization, will host a virtual breast cancer and cannabis conversation in honor of October’s annual breast cancer awareness month. 

“Breast Cancer and Cannabis: Considerations. Cautions. And Case Studies” will be a live webinar held Wednesday, October 6, from 2:00 – 3:30 p.m.. The free forum will feature a panel of multi-state Midwest women experienced with both breast cancer and cannabis, including leading Missouri cannabis patient advocates and product formulation experts. Breast cancer patients who are registered medical marijuana patients in their respective states, and receive guidance from one of the panel presenters will also join the conversation, sharing their valued perspectives and experiences. 

nuEra Cannabis, the Illinois owned and operated vertically integrated cannabis company, is sponsoring the educational event to complement nuEra’s “Pre-Rolls for a Cause” product and retail promotion. nuEra’s campaign commemorates breast cancer awareness month; it will donate proceeds from the promotion to Illinois cancer charities. Learn how you can support its initiative: nuEra Breast Cancer Awareness Fundraiser. 

“Illinois Women in Cannabis values being able to organize and host important conversations like this upcoming breast cancer awareness forum,” said the Executive Director of Illinois Women in Cannabis, Amor Montes de Oca. “IWC was founded the year Illinois approved medical use, so we’ve grown and evolved in tandem with the state’s cannabis program. Over these past seven years we’ve been able to expand our educational offerings, advocacy initiatives and community partnerships thanks to having active members and loyal support from cannabis businesses, like nuEra. This upcoming webinar reflects the important work IWC is able to do, thanks to its members and corporate sponsors,” Amor said. 

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Can You Use Medical Marijuana for Arthritis Pain?

The cannabis plant contains more than 540 chemicals, including more than 100 active chemicals known as cannabinoids that are only found in the world in the cannabis plant. The two most abundant cannabinoids are tetrahydrocannabinol (THC) and cannabidiol (CBD).

Products that contain significant amounts of the intoxicating ingredient THC are often referred to as “marijuana” which is a slang term. In this article, we use the proper scientific term “cannabis” throughout to refer to any products derived from the cannabis plant.

Many people anecdotally report cannabis helping them manage their arthritis pain, but most of the scientific evidence so far comes from animal or lab studies. Researchers are continuing to examine the potential benefits of cannabis for treating pain and other conditions such as anxiety and sleep disorders.

Keep reading as we dig deeper into the latest research examining the link between medical cannabis and arthritis pain. We also examine potential side effects and the best ways to take cannabis.

Medical cannabis is any cannabis or cannabis product used to treat a medical condition. Many people use cannabis to treat medical conditions such as chronic pain, anxiety, and sleep disorders. However, the Food and Drug Administration (FDA) hasn’t yet approved cannabis to treat any of these conditions.

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Terminally Ill Californians Will Have Access To Medical Marijuana In Hospitals

California Governor Gavin Newsom signed a bill on Tuesday requiring hospitals and other health care facilities to allow terminally ill patients to use medical marijuana, Marijuana Moment reported.

The governor approved the legislation, also known as “Ryan’s Law,” sponsored by State Sen. Ben Hueso (D), who had been pushing for this measure for years.

“It is inconceivable to me that, in a state where medical cannabis was legalized more than 25 years ago, those in deepest suffering receiving treatment in our state’s healthcare facilities cannot access this proven, effective and prescribed treatment,” Hueso disclosed in a press release. “Instead, terminally-ill patients in California healthcare facilities are given heavy opiates that rob them of their precious last moments with family and friends. This is a simple, yet critical, move that will provide relief, compassion, and dignity to terminally-ill Californians.”
In 2019, an earlier version of the bill was vetoed by Newsom due to confusion related to possible implications connected to allowing cannabis consumption in health facilities.

The issue arose over whether medical facilities in legal marijuana states can legally allow certain patients to use medical cannabis without jeopardizing the facility’s federal funding.

Hueso recently asked the head of the U.S. Department of Health and Human Services (HHS) to clarify the subject.

The Centers for Medicare and Medicaid Services (CMS) responded in a letter to Hueso that there are no federal regulations that specifically address the issue and that the agency was not aware of any cases where funding had been pulled due to a hospital or long-term facility allowing patients to use medical marijuana.

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Cannabis Provides Immediate Relief For Symptoms Of Depression, Other Mental Health Issues

According to a research study published by the University Of New Mexico and Releaf App in the Yale Journal of Biology and Medicine, cannabis flower may be effective in providing immediate relief for the symptoms of depression — a condition affecting roughly 1 in 5 adults in the U.S., and often leading to other ailments like cancer, substance use disorders, anxiety disorders, schizophrenia, dementia, diabetes, cardiovascular disease, and chronic pain. “The findings suggest that, at least in the short term, the vast majority of patients that use cannabis experience antidepressant effects, although the magnitude of the effect and extent of side effect experiences vary with chemotypic properties of the plant,” the paper reads.

The Research

The study, titled “The Effectiveness of Cannabis Flower for Immediate Relief from Symptoms of Depression,” was led by the founders of University of New Mexico’s Marijuana Research Fund, Jacob Vigil, Psychology Associate Professor at UNM, and Sarah See Stith, Economics Assistant Professor at UNM.

After reviewing 5,876 outcomes reported anonymously by 1,819 individuals tracking their cannabis use for treating depression through the Releaf App, the researchers concluded that, on average, patients reported an improvement in symptoms of nearly 4 points on a scale of 0 to 10, just moments after consuming whole, dried, natural cannabis flower – widely known as cannabis buds.

By means of comparison, readers should know that conventional pharmaceuticals used for the treatment of the symptoms of depression (like monoamine oxidase inhibitors, tricyclics antidepressants, selective serotonin-reuptake inhibitors, and selective norepinephrine reuptake inhibitors) normally take several weeks, or even months, to start causing significant relief. Furthermore, the study notes that the potential side effects associated with these traditional pharma products include sedation, agitation, anxiety, anorgasmia, demotivation, and suicidal ideation.

“One of the more interesting findings from this study is that cannabis flower with relatively high levels of tetrahydrocannabinol or THC is particularly associated with immediate reductions in the intensity of depressive feelings,” said Jacob Miguel Vigil. “The differences in time-to-effect and relative side effect prevalence across products and users could arise from other antidepressant and synergistic compounds in the plant beyond THC or cannabidiol (CBD), including minor cannabinoids, terpenes and flavonoids.”

Further Detail

Per the study, most of the patients using natural cannabis flower products to treat their depression symptoms reported antidepressant effects. However, the magnitude of these effects and extent of experienced side effects varied alongside the properties of each plant.

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Cannabis products are being sold as sleep remedies — here’s the evidence about their effectiveness

Problems with sleep are common. In recent research, 48 per cent of UK adults said sleeping badly had a negative effect on their mental health. For teenagers, this proportion was significantly higher — 66 per cent.The large number of people experiencing sleep problems makes for an attractive market. Some companies have seized the opportunity to provide remedies, including several manufacturers of cannabis products.

Changes to the way cannabis is regulated in many countries, including the UK, have helped the boom in cannabis products, with more people able to access these types of offerings — even if the cannabis compounds that can be used in sleep products in some countries are more limited than in others. In the U.S., where cannabis is fully legal in many states, California-based Ganja Goddess reported more than a sevenfold increase in revenue for its cannabis sleep products during the first year of the COVID pandemic.

But what is the evidence that cannabis products can help people get a better night’s sleep?

 

Cannabis and sleep

Sleep disturbance is a common feature of withdrawal from cannabis use, indicating there may well be a relationship between cannabis use and sleep. But we still don’t have a clear understanding of the mechanisms in the brain involved in this relationship.

The effects of cannabis are due to a group of chemicals in the drug called cannabinoids. These include cannabidiol (CBD), cannabinol (CBN) and tetrahydrocannabinol (THC). THC is the psychoactive substance in cannabis. CBN and CBD don’t cause you to get high in the same way.

In the UK, CBD products are available legally, providing they don’t contain more than 0.2 per cent THC. Retailers and suppliers make all kinds of assertions about the benefits of CBD products, including how CBD can improve sleep. There is some evidence to support these claims, but this is mainly based on animal and human observational studies rather than randomised control trials, where comparisons can be made between CBD and a placebo.

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Federal Grant Approved to Study Medical Marijuana Impact in Arkansas

A federal grant will help fund a study on the medical cannabis program in Arkansas. 

Thanks to $1.3 million courtesy of the National Institute on Drug Abuse, which is part of the National Institutes of Health, researchers affiliated with the University of Arkansas for Medical Sciences (UAMS) and Arkansas Center for Health Improvement will conduct what is being described as “a first-of-its-kind population health analysis of the medical marijuana program, combining eligible consumers’ cannabis purchase information with insurance claims records and other data sources to gain a more comprehensive understanding of the effects of cannabis on consumers’ medical care.”

The study, titled “Population-Based Analyses of Healthcare Utilization and Outcomes in Users of Medical Marijuana,” will “also examine the impact of COVID-19 on the Arkansas medical marijuana program, including changes in cardholder requests, product purchases, healthcare utilization and adverse events,” according to a press release from the Arkansas Center for Health Improvement, which is “a nonpartisan, independent health policy center that serves as a catalyst for improving the health of all Arkansans through evidence-based research, public issue advocacy and collaborative program development.”

“This is an exciting and unique opportunity for not only our state, but also the country, to investigate the effectiveness of cannabis for therapeutic use,” said Dr. Joe Thompson, co-principal investigator on this study, and the president and CEO of the Arkansas Center for Health Improvement. “While researchers have gathered scientific evidence on the use of cannabis for the alleviation of symptoms such as pain and anxiety, there is little evidence on how the amount, strain, potency and method of use affect a person’s health experience.”

Additionally, the study will also “incorporate six Arkansas-based data sources, including the Arkansas Healthcare Transparency Initiative’s Arkansas All-Payer Claims Database (APCD), Arkansas Department of Health medical marijuana patient registry data, medical marijuana dispensary purchase data, vital records, emergency department records and Arkansas State Police motor vehicle crash data,” with all the data being “de-identified with linkages utilizing the unique capabilities of the Transparency Initiative.”

The Arkansas Center for Health Improvement said that by “examining data for Arkansans who have qualified for medicinal use, this research will help inform the potential role of cannabis in medical therapy.”

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Medical cannabis trials in France show promise

The first results of a trial into using medical cannabis for pain relief that began in a hospital in central France in March are looking promising. 

Psychiatrist Dr Nicolas Authier, Chair of the Scientific Committee on Medical Cannabis, is in charge of the experiment being conducted at the University Hospital of Clermont-Ferrand. He had identified 20 patients as being suitable for participation.

One patient Mounir, 47, who suffered a stroke aged 21 and consequently struggled with painkiller addiction in trying to manage his neuropathic pain, told France 3: “I'm not yet completely relieved of the pain. There is some still, but it is nothing like what I felt before.”

The trial is part of a two-year nationwide experiment primarily designed to evaluate the best conditions of access to medical cannabis.

Dr Authier hopes that medical cannabis will then be legalised for patients whose suffering is poorly relieved by conventional treatments. 

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Why Medicinal Cannabis Could Signal the End of the Opioid Crisis

It may not come as a surprise to hear there is a global opioid crisis happening right now. Outside the UK and US, countries like Norway, Portugal, Sweden and Estonia are also experiencing opioid overuse and addiction. Carl Esprey look’s at why the humble marijuana plant used to create medicinal cannabis could signal the end of the opioid crisis.

In clinical trials, over 85% of UK patients reported that they found medicinal cannabis to be more effective in treating pain than opioids and other pain medicine, suggesting that prescribing cannabis for medical use could help resolve the global opioid crisis.

The Fight Against Chronic Pain

Millions of people across the world suffer from chronic pain in one form or another every day. Chronic pain lasts three months or longer and has a significant negative impact on a person quality of life. The Covid-19 pandemic has left many more people suffering from musculoskeletal pain after coming down with the virus and has reportedly caused those already experiencing chronic pain to suffer from more significant pain with what is now known as long-Covid.

According to the British Medical Journal (BMJ), “chronic pain affects between one-third and one-half of the population of the UK, corresponding to just under 28 million adults, based on data from the best available published studies. This figure is likely to increase further in line with an ageing population.” Science Daily says, “Researchers report that 50.2 million (20.5 per cent) U.S. adults experience chronic pain based on analysis of the new NHIS data. They estimated the total value of lost productivity due to chronic pain to be nearly $300 billion annually.”

Traditionally, certainly since the 90s, opioids have been the go-to for physicians to prescribe for pain symptoms. The unfortunate reality is that opioids are highly addictive, which has led to people taking more than the recommended dose, taking them too frequently and in some cases overdose, leading to death! For this reason, even the UN is looking into the global opioid crisis and considering how it is best managed.

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CBD usage in the animal sector continues to grow. Here's why.

In the United States, CBD usage is increasing, both among pet owners and manufacturers of CBD products. In fact, according to market research by Packaged Facts carried out in August 2018, among those who said they had bought CBD products, the proportion of dog owners who said they had done so increased by 36 percent compared to 24 percent for cat owners.
 
The increased usage is mainly due to the widespread availability of CBD-based products marketed for animals now more than ever before, including treats and supplements that feature patented product technology.
 
Many pet owners seek CBD products for their beloved pets because of perceived benefits, even though there is still a lack of hard scientific evidence that CBD-based effects are beneficial to animals.
 

The Blossoming Hemp Trend

One trend gaining traction in the U.S. is hemp production, which has become legal at the federal level, but with complicated state-by-state regulations that vary depending on whether or not the plant being produced is marijuana or hemp. CBD products are typically derived from hemp, but it is important to note that under current federal laws, CBD can only come from hemp acquired through legal means.
 
In addition to being marketed for their natural calming qualities, CBD pet treats have been promoted as helping with muscle and joint pain. They provide relief from arthritis and other ailments common among older pets or those who put on more pounds than they can easily manage. A growing number of CBD products are also marketed to relieve anxiety, especially around events like fireworks.
 
The 2016 National Pet Owners Survey by the American Pet Products Association (APPA) found that one in five U.S. pet owners used either a dog or cat supplement that featured CBD oil and other cannabinoids and terpenes, up from just one in ten in 2015.
 
Nearly half of all CBD-related products were marketed as solutions to ease anxiety.
 
The Packaged Facts report also found that CBD-containing pet supplements were the most popular (salves, treats, and oils) and, with nearly 60 percent of those surveyed who bought these products saying they'd used them on their dogs. Only 12 percent had used them on cats, but because there are so many more cats than dogs in the country, that amounted to a significant number.
 

Effects of CBD on Pets: Unravelling Facts from Fiction

But what do we know about how and whether CBD affects the health and behavior of our pets?
According to some veterinarians, positive anecdotes are not enough. They urge pet owners to seek out veterinary guidance if they are considering using CBD on their animals. Veterinarians say that there is not enough research to show how CBD might affect animals — and they warn that sometimes the products might be harmful.
 
The FDA has not approved any product containing CBD for use in pets, and it cautions pet owners to make sure their veterinarians agree of any such products before trying them out on an animal in their care.
"Veterinarians must be cognizant that there are potential risks associated with the use of CBD in dogs, especially if these products have other active ingredients or additives that can cause side effects," said Dr. Jerry Klein, a veterinarian with the American Veterinary Medical Association (AVMA).
"While it is true that pets experience many of the same medical conditions as people, they may also have other underlying diseases that alter the way their bodies respond to treatment," Klein said. "We recommend pet owners work closely with their veterinarians when considering CBD for their pets."
Many vets don't know enough about CBD yet, and some are still uncomfortable with its use in pets. Others say they don't want to put their patients on a new medication without first understanding how it might interact with other drugs the animal is taking.
 

Moving Forward

Still, some veterinarians are turning to CBD products, including Colorado-based veterinarian Dr. Debbie Benson, who has switched her dog over to a daily CBD regimen. Benson said that she had seen positive results in several of her veterinary clients' pets since they began giving their animals CBD oil on top of other conventional treatments; they've been able to lower their pets' dose of pain medications or anti-anxiety meds.
In addition, some pet owners have reported CBD helped ease the side effects of chemotherapy in animals with cancer.
Some pet owners also use a hemp extract called Real Scientific Hemp Oil (RSHO), rich in CBD but much lower in THC. This extract has a known safety profile and is available by prescription from veterinarians.
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Cannabis use in colorectal cancer survivors

Currently, 18 states have legalized the recreational use of marijuana and 36 states have legalized the medicinal use of marijuana. Many cancer patients (16-24%) use cannabis to curtail symptoms related to cancer or cancer treatment. Dr. Newcomb, the first author of the publication, stated that “marijuana has some important properties that motivate cancer patients to use it for nausea and vomiting, appetite, pain, fatigue.”  Previous studies indicate that cannabis is widely used among cancer patients with late-stage disease or with other poor mental or physical health states.  Due to improvements in early detection and cancer treatments, the number of cancer survivors will expand by one million per year, which includes at least 150,000 colorectal cancer (CRC) patients.  Therefore, about 2.7 to 4 million survivors may intentionally use cannabis for symptom management or other reasons. Presently, cannabis use and its side effects are not monitored among cancer patients and survivors. The Newcomb Group, from the Division of Public Health Sciences, evaluated the demographic, behavioral, and clinical characteristics of cannabis use among colorectal cancer patients from Washington State. CRC has a high prevalence and several treatments with side effects thus, CRC provides a good model for understanding cannabis use among men and women with cancer. This study is published in Cancer Causes & Control.  

The participant data was collected from a population-based cancer registry, the Puget Sound Surveillance, Epidemiology, and End Results registry (SEER).  The registry consists of data from cancer cases in the 13-county Puget Sound SEER region. Patients were contacted by mail at least 3 months post-diagnosis. If interested, participants provided informed consent.  The participants completed surveys via telephone interview, online portal, or a paper questionnaire.  All cannabis use questions were obtained by close-ended questions. Patients also reported quality of life measures through the Functional Assessment of Cancer Therapy-Colon (FACT-C); which asked questions pertaining to physical, functional, social, and emotional wellbeing as well as concerns around colorectal cancer.  Tumor location and stage were collected for participants.  Logistic regression was utilized to calculate odds ratios and 95% confidence intervals to compare the odds of “current cannabis use” in relation to demographics, health behaviors, quality of life assessments, and tumor characteristics. 

The analytical study population included 1,433 participants. Current smokers (95% CI=1.21-2.98) were two times as likely to use cannabis than former smokers (95% CI=1.38-2.45).  Light-to-moderate and heavy drinkers were more likely to use cannabis compared to non-drinkers and occasional drinkers.  Poor quality of life scores was more likely to be associated with current cannabis use (OR=1.52, 95% CI=1.14-2.04).  Participants with distant stage CRC had 3-fold greater odds of using cannabis than those with localized CRC (95% CI=2.03-4.17). 

In conclusion, comprehensive research is needed to identify various types of cannabis use, their patterns, and reasons for use among cancer survivors. Most CRC patients consumed cannabis by smoking.  This act could increase the risk of negative pulmonary outcomes; however, the current research is limited.  Dr. Newcomb concluded: “Although this area of research is underfunded, we used this data to motivate the submission of a CCSG pilot study and now I’ve joined with 11 other cancer centers across the US to form a consortium measuring cannabis use in cancer patients.” The results from the present study suggest that cannabis use is used to manage a variety of cancer-related symptoms and treatments.  The Newcomb Group concluded that “there is a strong and timely need for additional research to understand the benefits and harms of cancer patients’ cannabis use in order for patients and doctors to make informed, evidence-based decisions about the use of cannabis for symptom management.”

This research was supported by the National Institutes of Health/National Cancer Institute.
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A closer look at the fine print of cannabis

 

Last week, a couple of developments took place at both the state and global levels regarding the regulation of cannabis in regards to it being something that humans put into their bodies.

 

LABELING GETS SPECIFIC

The Washington State Liquor and Cannabis Board issued a policy statement last week clarifying the rules surrounding structure or function claims made about cannabis-infused products. Those are essentially claims about what a product does. For example, a bottle of daily multivitamins may say something about maintaining heart health, or a vitamin C supplement could mention that it supports the immune system. What could not be said, however, is that either product is meant to diagnose, treat, cure or prevent any disease.

As a matter of fact, when it comes to cannabis, products making structure or function claims — like a CBD tincture formulated for pain relief — must explicitly state on the product's packaging that it is not meant to diagnose, treat, cure or prevent any disease.

Any packaging that includes a structure or function claim must include this exact phrase, "this statement has not been evaluated by the State of Washington. This product is not intended to diagnose, treat, cure or prevent any disease."

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Does Cannabis Make You More Empathetic?

Cannabis and empathy? You might be wondering, “what does empathy have to do with cannabis? I thought stoners were supposed to be apathetic.” Well, the answer might surprise you.

Studies suggest cannabis actually positively impacts our ability to process emotions. Cannabis opens up the potential to understand others better and be more aware of their feelings, according to experts.

However, we are not saying that you are a joint away from sainthood. As experts point out, such cannabis-induced empathy depends significantly on the cultivar type, user intention, and the amount of cannabis consumed. Take too much, and you may in turn suppress your emotions.

Note that I have used the words “empathy” and “compassion” synonymously for this article. Accordingly, it is essential to note what empathy means and what is its physiological nature.

Our neural networks let us be more receptive to the needs, experiences, and desires of other people. It enables us to appreciate other people’s emotions and feel at one with them, understand their point of view, and understand how and why it differs from ours’.

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