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Is Mixing Cannabis And Prescription Drugs A Good Idea?

Taking CBD or marijuana might help your pain, but could be making the other drug(s) you’re taking more toxic.

It is widely known that cannabis has many medicinal benefits, with managing chronic pain, epilepsy, anxiety and treating the symptoms of PTSD among them.

However, in the case of cannabinoids, a group of substances found in the cannabis plant, there is a risk that combining it with other prescription drugs could pose harmful drug-drug interactions, suggests new research undertaken by scientists at Washington State University (WSU).

The researchers looked at cannabinoids and their major metabolites found in cannabis users’ blood and found that they interfere with two families of enzymes that help metabolize a wide range of drugs prescribed for a variety of conditions. As a result, either the drugs’ positive effects might decrease or their negative effects might increase with too much building up in the body, causing unintended side effects such as toxicity or accidental overdose.

The findings examined the interaction between three of the most abundant cannabinoids – tetrahydrocannabinol (THC), cannabidiol (CBD), and cannabinol (CBN).

While more research is essential, the authors suggested that caution should be taken when using cannabis with prescription drugs.

“Physicians need to be aware of the possibility of toxicity or lack of response when patients are using cannabinoids,” said Philip Lazarus, senior author on the paper and Boeing distinguished professor of pharmaceutical sciences. “It’s one thing if you’re young and healthy and smoke cannabis once in a while, but for older people who are using medications, taking CBD or medicinal marijuana may negatively impact their treatment.”

Lazarus added, “It’s one thing if you’re young and healthy and smoke cannabis once in a while, but for older people who are using medications, taking CBD or medicinal marijuana may negatively impact their treatment.”

 

The Findings

Researchers used manipulated human kidney cells and confirmed their results in human liver and kidney specimens in which enzymes were present.

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Colorado Marijuana Tax Revenue Breaks Annual Record

Colorado's annual marijuana tax revenue haul has already reached a new high for the seventh straight year, according to the latest data from the state Department of Revenue.
The DOR's latest monthly report on marijuana tax revenue shows that November's $32.5 million in combined marijuana taxes and fees pushed 2021's overall total past $392.8 million. That's nearly $5.4 million more than the previous record, made in 2020 — with one month left to spare.

Colorado collects four different forms of marijuana taxes and licensing fees from the legal marijuana industry: a 15 percent tax on recreational pot sales, a 15 percent excise tax on wholesale marijuana, a 2.9 percent sales tax on recreational and medical marijuana purchases, and various licensing and application fees that state-approved marijuana businesses must pay.

According to DOR records, this year's averages in each of the four marijuana tax and fee categories are higher than those in 2020. But despite 2021 already being the highest year yet for pot tax revenue, the state hasn't passed last year's sales figures, judging from DOR data.

So far, the DOR has only released dispensary sales figures through the month of October; they total just over $1.9 billion. After calculating sales amounts based on marijuana tax rates and November's reported tax revenue, sales figures for the first eleven months of 2021 should approach $2.075 billion.

In 2020, Colorado dispensaries sold just over $2.19 billion, and this December's sales figures are virtually guaranteed to put 2021 over that mark. Dispensaries grossed over $186.3 million in sales in December 2020, according to the DOR, and sales of just around $120 million would break 2020's record.

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'El Chapo's' errand runner — a key to the kingpin's ultimate capture — sentenced in San Diego

As Mexican and U.S. forces closed in on Joaquin "El Chapo" Guzmán Loera in the winter of 2014, they set out first to find the man they hoped would unlock many of the drug kingpin's secrets, and ultimately his whereabouts.

Characterized as Guzmán's personal assistant, Mario Hidalgo Arguello was intricately involved in the fugitive's comings and goings. Hidalgo's nickname in the Sinaloa cartel was "El Nariz," named for his prominent nose, which made him easily identifiable when authorities tracked him down at a party in Culiacán one night and demanded a tour of Guzmán's hideouts.

Indeed, Hidalgo led the Mexican Marines and a U.S. drug agent to the safe house where Guzmán was holed up, but he narrowly escaped through a tunnel under the bathtub.

Still, authorities stayed on the trail, capturing Guzmán a week later at a Mazatlán hotel.

While Hidalgo's legacy will be forever linked to the hunt for one of the world's most wanted drug lords, his official criminal record is silent on the matter and instead lists a single marijuana trafficking conviction.

On Monday, a San Diego federal judge sentenced Hidalgo to seven years in prison in the case, which involves a conspiracy to import marijuana aboard a San Diego yacht. U.S. District Court Judge William Hayes followed the joint recommendation of prosecutors and the defense in handing down the sentence — a departure from the 10-year mandatory minimum term he was facing.

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Drinkable weed: The newest trend in craft brews

Cannabis-infused beverages are gaining momentum

Inside a small garage near Golden is another potential budding American success story.

“Apple computer started in a garage. Microsoft also started in a garage,” Keith Villa said.

“This location is exactly 10 minutes to the front door of Coors. I drove it for 32 years.”

Villa’s name might sound familiar. He founded Blue Moon Brewing Company under the Coors brand in 1995.

“My claim to fame is that I started Blue Moon Brewing Company,” Villa said.

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Village of Dundee opts out of recreational marijuana indefinitely

Leaders in the Village of Dundee say they are willing to listen to proposals for recreational marijuana establishments in their boundaries, even as they unanimously voted to drop the sunset clause of the village's Prohibition of Marijuana Establishments Ordinance.

On December 7, village council approved the re-adoption of the ordinance with an amendment that removed the sunset clause, which required them to re-adopt the ordinance every year. Dundee had been using the sunset clause as a way to keep the opt-out temporary, but Village Council President Andrea Hickey said the decision to remove the clause was made after the village almost missed its deadline to re-adopt the ordinance last year.

"The ordinance still says that (recreational marijuana establishments) would be prohibited, but the sunset clause would be removed," Hickey said.

"The ordinance would no longer sunset; it would just be in there as prohibited. What happened last year is we almost forgot it, we had to throw it on the agenda."

Additionally, Hickey said she has recently had some discussions with fire departments in municipalities that do allow recreational marijuana establishments. Those discussions yielded a new reason why she believes council doesn't need to allow these facilities in the village at this time.

 

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European Union Increases THC Level For Industrial Hemp. Why Does It Matter?

The European Parliament approved on November 24 to increase the THC level from 0.2% to 0.3% for hemp crops used for industrial purposes.

The rise of the THC level for industrial hemp is part of the measures of the new Common Agricultural Policy (CAP) reforms, which will enter into force in 2023. 

Farmers may receive EU subsidies if they use hemp varieties registered in the EU catalog with a maximum THC level of 0.3%.

The European Industrial Hemp Association (EIHA) has made this achievement possible, representing the common interests of European hemp farmers.

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LEGISLATURE APPROVES FUNDING TO COMBAT ILLEGAL CANNABIS OPERATIONS

On Monday, the Oregon State Legislature approved funding to combat illegal cannabis operations in the state.

SB 893 provides $25 million to local law enforcement agencies to address unlawful marijuana cultivation or distribution operations.

Senate Republican Leader Tim Knopp said, “It’s clear that law enforcement needs more help to stop these dangerous illegal operations. This package gives our county partners the resources they need to hire the law enforcement and water masters to oversee the huge task they have in front of them”.

Democratic State Senator Jeff Golden said “Illegal cannabis operations in Southern Oregon have been using our limited water supply, abusing local workers, threatening neighbors and negatively impacting businesses run by legal marijuana growers. This is urgent funding we need right now to protect our agriculture industry, a pillar of Oregon’s economy and the Rogue Valley’s quality of life”.

SB 893 passed on unanimous votes in both the Senate and the House. Lawmakers covered a number of other topics in bills passed in Monday’s one-day special session.

 
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NDSU student's sugarbeet weed control project expands access to effective herbicide

The research of North Dakota State University graduate student Emma Burt paved the way for an emergency exemption that allowed sugarbeet producers to control water hemp in their 2021 crop with an herbicide previously used on soybeans.

After screening Ultra Blazer for use in sugarbeets , North Dakota State University Extension sugarbeet agronomist Thomas Peters turned over the project to graduate student Emma Burt, who studied and reported on the results of her project over Zoom meetings to sugarbeet cooperative representatives from across the United States for about a year. 
Burt, who is working on her master’s degree in agronomy at NDSU, was assigned by Thomas Peters, NDSU Extension sugarbeet agronomist, to study the efficacy of Ultra Blazer in water hemp control in sugarbeets.

Peters, whose role with Extension includes weed control in sugarbeets in North Dakota, Minnesota and eastern Montana, for the past nine years has worked to control pigweed species, including water hemp. Through Peters’ weed research, which involved screening herbicides used for non-sugarbeet crops, he learned that Ultra Blazer showed promise for water help control in sugarbeets.

Ultra Blazer was a popular herbicide for broadleaf weed control in soybeans during the 1990s, Peters said.

After screening Ultra Blazer for use in sugarbeets , Peters turned over the project to Burt, who studied and reported on the results of her project over Zoom meetings to sugarbeet cooperative representatives from across the United States for about a year.

Burt’s research showed that sugarbeets tolerated Ultra Blazer and that it controlled water hemp in the crop.

During one of the Zoom meetings Burt had with the sugarbeet cooperatives, a cooperative administrator suggested that Ultra Blazer’s label should be approved for sugarbeets, Peters said.

In early 2021, Peters applied to the U.S. Environmental Protection Agency for an emergency exemption of Ultra Blazer, citing the poor control of other herbicides, which rely on rainfall for activation, during the 2020 dry growing season.

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Need to pass that cannabis drug test? Four tips for safely flushing out THC

Despite cannabis becoming legal in more U.S. states, there are still organizations that ask for drug tests. It could be a school, a prerequisite for a job or something else. For regular cannabis users, it’s important to know how these tests work and how to flush the THC out of one’s system.

When cannabis is consumed, THC stays in the body for a long time, much longer than that “high” feeling. Matters get more complex once one considers that there is not yet a precise way of knowing exactly how long THC will stay in a person’s system, taking into account body weight, metabolism, body fat, physical activity, frequency of use, potency of strain and other factors.
 
It’s also important to know which drug test will be administered since THC’s presence varies depending on the type of body sample being analyzed. For example, saliva tests may measure the presence of THC that was consumed a few days ago, while hair samples can show THC consumed three or more months ago.

Here are four safe ways to help a person register a clean drug test. Be aware that the more time a person has before the test to prepare, the more likely the approach taken will be successful. Of course, the best way to test clean for an upcoming test is to steer clear of weed.

Dilution method

This method works best for tests for urine tests to measure THC. Dilution is aid to work best when done at least three days ahead of time and basically involves drinking a lot of water. This increases urine flow, with the ideas being that will dilute the THC concentration in the sample provided. Some maintain diuretics like cranberry juice and coffee will help speed the process.

Since drinking copious fluids will make a person’s urine fairly clear-coloured, the National Organization for the Reform of Marijuana Laws reports taking vitamin B2. This will add some yellow colour to the urine yellow.

Test oneself

If a test is coming up, consider testing at home ahead of that time. Many drug abuse centers provide drug tests for free and there are also pharmacies, which sell home kits for drug testing.

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Was the 'pipe-weed' in Lord of the Rings cannabis?

Consider that Hobbits are peaceful, big on gardening and possess what could only be described as voracious appetites.

It may be a bit of a stretch, but a recent article on the Comic Book Resources (CBR) website suggests those smoke-loving Hobbits familiar to all fans of The Lord of the Rings may be opting for a bit of green in their regularly lit pipes.

The website asks: Is their pipe-weed Middle-earth’s version of cannabis?

CBR clearly acknowledges that J. R. R. Tolkien — known to love his own pipe smoking, albeit the more traditional type, and whose habit may have inspired the relaxing pastime of the Hobbits and Gandalf — has said the smoked material is tobacco, not cannabis.

That said, the website still sees what it calls some “wiggle room” regarding that assumption. Citing The Lord of the Rings  appendices, CBR notes that the Hobbits “imbibed or inhaled, through pipes of clay or wood, the smoke of the burning leaves of a herb, which they called pipe-weed or leaf, a variety probably of Nicotiana.”

While Nicotiana includes tobacco, according to Gardening Know How, CBR suggests the use of “probably” opens the door to pipe-weed being something other than tobacco. Something, say, like cannabis.

There are also some attributes and habits of the Hobbits that perhaps make the link somewhat more believable.

Consider that Hobbits are peaceful, big on gardening and possess what could only be described as voracious want of food, what with seven daily chances to chow down from breakfast at 7 a.m. to supper at 9 p.m.

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Mike Tyson's Cannabis Products 'Personally Tested And Approved' By The Legendary Boxer Reach California

Legendary heavyweight boxer Mike Tyson’s cannabis brand is now available in California. His cannabis company Tyson 2.0 confirmed Tuesday that its premium quality cannabis line is now available at more than 100 retailers across The Golden State. (Originally posted by Benzinga)

 “We are focused on bringing Tyson 2.0 premium cannabis products to retailers nationwide and after a strong debut in Colorado, we are now available across California in over 100 retail outlets marking a major milestone for the company,” Adam Wilks, CEO of Tyson 2.0 told Benzinga.

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‘Zero tolerance’ warning over medicinal cannabis

A warning has been issued by a local medical cannabis clinic that it will ban patients trying to use what it called ‘underhand’ means to try to obtain ‘double medication’.

Medicann – which operates clinics in Jersey, Guernsey and the Isle of Man – recently posted a statement on Facebook after what it described as a ‘potential issue’ affecting one of its clinics.

The company stressed that it was not acceptable to obtain multiple prescriptions from different sources simultaneously, and it advised patients currently obtaining prescriptions from the UK that they should not attempt to obtain one from Medicann until they were ready to switch to a local clinic and pharmacy.

A spokesperson for Medicann told the JEP that they would take a ‘zero tolerance’ approach to anyone who tried to misuse their products or services

The company’s statement continued: ‘Medicinal cannabis is a regulated medicine and as such, must be treated with the same respect and caution as other medication. Our expert doctors take great care in prescribing the right products at the right strengths and the right amount. For anyone to try and receive double the medication by being underhand is unacceptable and could result in patients being banned from the clinic/s. Our team at Medicann has one main aim, that is to support and help people access medicinal cannabis for treatment and care. We will not condone any form of abuse of our service and will take suitable action to ensure our staff and patients’ safety.’

Despite the statement not being produced in response to comments made by the police and Customs last week, it follows intelligence gathered by Jersey Customs suggesting that efforts had been made in the Island to sell drugs obtained by prescription to others. And although police chief Robin Smith said that they had received no complaints, he said he thought it was ‘inevitable’ that they would in the future.

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Whoopi Goldberg CBD Gummies Reviews – Is it Fake Gummies Or Trusted?

Whoopi Goldberg CBD Gummies

Being in good physical and mental health is essential to living an active and healthy life as you get older. Mental and physical well-being is a blessing that most individuals begin to lack as they become older. Ailments, which wreak havoc on a person’s internal organs and make them seem and feel old, are the primary cause of this unwelcome process of ageing.

The Whoopi Goldberg CBD Gummies we’ve developed today can alleviate a wide range of symptoms associated with the ageing process, including anxiety, depression, insomnia, joint pain, and stress. All of these ailments can be alleviated with this medication, which is enriched with CBD. It has become a worldwide sensation because of its ability to alleviate tension and anxiety by calming the mind and promoting maximum relaxation.

Having a healthy, peaceful, and relaxed mind is essential to living a long and healthy life, which most individuals lack. Smoking has become ingrained in many people’s lives, including children and teenagers. These issues can be addressed with This product, a ground-breaking new product designed for teenagers and young adults over the age of 18. To back up their claim, the developer of this product claims that it can help people kick the habit for good.” Organically grown natural ingredients are used to produce this product, as are hemp plant extracts, which have undergone extensive testing and study before being included.

If you want to achieve the best results, you should always choose natural goods, and This product is the potent formula that meets all of these requirements. Wisdom and intelligence are gained in the second part of life due to life experience. Ailments are many things that come with age, along with virtues like patience, wisdom, and experience. Anxiety, despair, and other mood disorders, as well as joint and back pain, are all common complaints among the elderly, which is why we suggest trying This product to help you reclaim your quality of life.

Whoopi Goldberg CBD Gummies: What Are They?

Full-spectrum gummies, like This product, can be used for various purposes. According to the manufacturers, these gummies are designed to provide natural pain relief. According to hundreds of customer reviews, this product does far more than alleviating pain and inflammation. For any possible benefits of CBD oil, you can rely on these all-natural and delectable gummy bears.

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Lamar Marijuana Ballot Survives Challenge

“The Elections Division of the Secretary of State’s Office (Division) moves the Deputy Secretary of State to dismiss the above-entitled Lobbyist Complaint on the grounds that Complainant failed to specifically identify violations of Colorado lobbyist laws under section 24-6-301, et seq, C.R.S.”

Belinda Sturges approached the Lamar City Council during a public meeting this past November, asking about the legitimacy of the petitions filed with the City of Lamar which placed questions 2A and 2B on the November General Election before Lamar residents.  Those ballot questions dealt with establishing levels of a tax placed on sales of recreational and medical marijuana and in the other portion, for voters to approve or reject the public sale of marijuana products, among other allowances.  Both questions passed.  Lamar Mayor Crespin and City Attorney, Lance Clark, explained at that time, that they were aware of the questions pertaining to the validity of the petitions, but as the matter was under legal review, they could not provide her at that time with any answers to her questions.

The State Elections Division noted, “On November 10, 2021, Belinda Sturges (Complainant) filed a Complaint with the Division, under Lobby Rule 5. 1.1 alleging that Cindy Sovine (Respondent) violated Colorado lobbying laws.  Specifically, Complainant alleges that (1) Respondent engaged in lobbying without reporting her income on TRACER, (2) Respondent circulated petitions that were insufficient, (3) the parties carrying the petitions were not disclosed, and (4) Respondent “represented she was working for SOCO Rocks who only held a name reservation with the SOS.”

“On November 10, 2021, Respondent submitted a response to the Complaint, what included several supporting documents including a scope of work agreement for ballot campaign management services, communications with the Secretary of State’s office, communications with the City Clerk of the City of Lamar, and messaging related to the ballot question.”

“The Division moves to dismiss the Complaint on the grounds that Complainant failed to specifically identify violations of Colorado lobbyist laws under section 24-6-301 et sec, C.R.S.”

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High school buddies launch CBD company in Sandston

A trio of old high school buddies are behind a new player in the local CBD scene.

VA Harvest, which sells CBD extracts and cremes in stores and online, launched in November.

The company has a budding retail presence, with products on shelves at grocery store Ellwood Thompson’s and Fan wellness store Blossom RVA, co-founder Bill Wingfield said. The company plans to expand locally and across the southeastern part of the country.

It also sells products through its website. The company’s 30 ml extracts are priced at $98 on the site, the same price as its 1 ounce topical creme.

VA Harvest plans to launch CBD products aimed at animals in the spring.

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A Michigan company is expanding in Missouri’s burgeoning marijuana market

Missouri’s cannabis industry continues to attract businesses and create jobs.

A multistate company based in Michigan is opening a cannabis processing facility this month in St. Louis. It is also partnering with another company on a cultivation operation in O’Fallon.

“I think Missouri is a rather competitive market,” said C3 Industries CEO Ankur Rungta.

“We think there is a healthy amount of demand for our products in a market like this.”

C3 Industries already has a foothold in Missouri. The company has opened medical marijuana dispensaries in St. Charles, Columbia, St. Robert, Cape Girardeau and Sunset Hills.

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Cannabis Is Starting to Get Hit by Supply-Chain Shortages

Lunar New Year is a looming threat

Getting basic materials like ceramics, stainless steel and computer chips from China has gotten so difficult that its about to hit one of the few industries that has so far been insulated from supply-chain woes: U.S. cannabis.

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Greenville planners send marijuana rules to council

Ordinances would permit medical marijuana but continue to prohibit adult-use

A series of ordinances that will regulate the commercial sale, growing, processing and more of medical and adult-use marijuana will now make their way to the Greenville City Council.

However, not everyone in the community — from residents to business owners both opposed and in favor of creating a commercial market of legal marijuana — is happy with the direction the city is going.

In April, the City Council sent four ordinances — two zoning ordinances and two regulatory ordinances — to the Planning Commission to be evaluated and reworked to the city’s liking for potential adoption into law.

During Thursday’s Planning Commission meeting, after months spent on reviewing and altering amendments to the city’s zoning ordinances, members of the commission reached a consensus, voting unanimously on five separate motions — on two regulatory ordinances and three ordinance amendments — to be recommended for approval by the City Council.

“The City Council has crafted these ordinances, they will enact these ordinances, but they asked the Planning Commission to review the language they created and we have done that,” Commission Chairman David Ralph said.

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Betting on themselves, sisters-in-law open Pepperell’s first cannabis dispensary

Nearly two years after they made their initial pitch to the Select Board, sisters-in-law Priyanka and Tejal Patel finally saw their dream made a reality as they opened Uma Flowers, Pepperell’s first recreational cannabis store last week.

Opening ceremony and ribbon cutting for Uma Flowers, Pepperell’s first cannabis dispensary, from left, Select Board chair Margaret Scarsdale, town planner Jenny Gingras, town administrator Andrew MacLean, and co-owners Priyanka Patel and her sister-in-law Tejal Patel, both of Waltham. SUN/Julia Malakie

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The science behind cannabis and the munchies

Numerous studies attribute increased appetite to a poor sleep schedule.

Having access to favourite meals or snacks is essential to any successful cannabis session. Most people are familiar with the concept of getting the munchies after consuming marijuana, but why it occur still remains a mystery to many.

But despite the munchies seeming like one of life’s unsolved mysteries, there are a few scientific reasons that can explain what causes it. Here are a few factors that help explain why people get the munchies after consuming marijuana.

The role sleep plays in promoting the munchies

Want to keep the munchies at bay? Then considering making sure to get enough sleep. Numerous studies attribute increased appetite to a poor sleep schedule.

According to a 2019 study, a lack of sleep can bring on the munchies in the same way consuming marijuana can. This seems to be because sleep restriction causes increased endocannabinoid levels in the blood that leads to hunger pangs, specifically for high-calorie foods.

“We found that sleep restriction induced qualitative changes in food intake, biasing choices toward energy-dense options, without altering total calorie intake,” wrote researchers.

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